Journal Reviews
Post hoc analysis of the CANTREAT randomised trial
CANTREAT, a Canadian multicentre two-year randomised trial compares treat and extend treatment (T&E) relative to the monthly administration of Ranibizumab in nAMD. Two-hundred and eighty-five treatment-naïve patients with nAMD were randomised to receive either a once-monthly dosing or T&E regimen...
Patient reported outcomes in adolescents with inherited retinal diseases
This was a two-centre validation study of two sets of patient reported outcome measures (PROMS) for adolescents (13-17- years-old) with inherited retinal diseases. The measures were the Michigan Retinal Degeneration Questionnaire (MRDQ) and the Michigan Vision-Related Anxiety Questionnaire (MVAQ). Both...
Intraocular pressure changes following TOHM washout
This retrospective study between 2008 and 2019 of 110 eyes with primary open angle glaucoma (POAG), 33 eyes with ocular hypertension (OHT) and 43 eyes with uveitic glaucoma (UG) evaluated the changes in intraocular pressure (IOP) following topical ocular hypotensive...
Visual and refractive outcomes and complications in FLACS versus CPS cataract surgery
This is a randomised, controlled study of 110 paired eyes from 55 patients that were randomised into either femtosecond laser-assisted cataract surgery (FLACS) or conventional phacoemulsification cataract surgery (CPS) groups. Visual, refractive outcomes, intraocular pressure (IOP) and complications were compared...
Effect of low-dose atropine on myopia progression
A randomised study to evaluate the effects of 0.01% and 0.02% atropine eye drops (one drop once nightly to both eyes) on myopic progression, pupil diameter and accommodative amplitude in myopic patients. Four hundred myopic children were divided into three...
Anatomical and functional outcomes following switching from aflibercept to ranibizumab in NARMD
This is a six-month, prospective, single-arm study in the UK and Germany. A total of 100 patients were enrolled (one in the primary failure group, 99 in the suboptimal treatment response group), treated three-monthly intravitreal ranibizumab injections (0.5mg), and then...
Intravitreal bevacizumab vs. triamcinolone in patients with DMO at the time of cataract surgery
This prospective, single masked randomised control trial (RCT) compared visual and anatomical outcomes when either intravitreal bevacizumab (BVB) or triamcinolone (TA) was administered at the time of cataract surgery and at subsequent review, if required, in patients with diabetic macula...
